Are You Getting Enough Vitamin B1 To Help Fend Off Alzheimers?

The ConversationA feeling of apathy or being a little forgetful from time to time is nothing unusual. But for some, this could be an early sign of not getting enough thiamine (also known as vitamin B1). Long term, this can have serious consequences, including an increased risk of developing Alzheimers disease.

There is often a fatalistic attitude towards Alzheimers disease, with the belief that its a consequence of old age or its in our genes. But most old people dont get Alzheimers disease, and its now clear that decisions made about lifestyle and diet play a huge role in singling out those who will and those who wont develop the disease.

Ensuring your diet contains enough B vitamins is one of those crucial dietary decisions. And the central role of thiamine is now becoming apparent. The brain needs thiamine to use glucose for energy, and without adequate thiamine, brain cells die. The brain also needs thiamine to make acetylcholine, the main neurotransmitter that is deficient in patients with Alzheimers disease. Thiamine levels are frequently low in patients with Alzheimers disease and the early stages of cognitive decline, and there are trials underway to see if taking thiamine derivatives can reduce the symptoms of this disease. The evidence is now pretty clear: a healthy brain needs an adequate supply of thiamine.

Getting enough thiamine

So how can you be sure you are getting enough of this essential brain vitamin? In the UK, thiamine is added to fortified cereals and bread, and other good sources include whole grain cereals, pork, trout, peas and beans. Government surveys in the UK present a generally reassuring picture, suggesting that for most people their thiamine intake is sufficient. But these surveys only report average intakes, and do not take into account groups who, for one reason or another, may be vulnerable to thiamine deficiencies.

One of the groups vulnerable to thiamine deficiencies is the elderly. And there are other groups, too, such as the steadily increasing numbers of people who avoid most cereal products (such as bread and pasta) because of gluten intolerance. These food products are the main source of thiamine in the average UK diet, so its not surprising that many gluten-intolerant people are thiamine deficient. Fortifying gluten-free alternatives with thiamine and other vitamins would be an obvious solution, but, unfortunately, this is not usually done. Followers of the Paleo diet also avoid cereal products, leaving this group vulnerable to thiamine deficiencies as well.

Pork is an especially good dietary source of thiamine, but many people do not eat pork. Also, if you prefer your pork as sausages rather than fresh meat, then you are waving goodbye to most of the thiamine, since, in the UK, pork sausages are preserved with sulphites that destroy the thiamine. Some countries, such as the US, take a more sensible approach and have banned the use of sulphites in sausages for this very reason. Isnt it time that the UK also removed sulphites from sausages and other foods where it is not necessary?

Is it time the UK banned sulphites from sausages? Treacle creative/

Sausages are also very popular as part of ready meals. Ready meals are a rapidly increasing sector of the food market, but there is no requirement to label their vitamin content. This is especially concerning for the many, such as many older people, who rely on ready meals for a large part of their daily vitamin intake.

And its not only sausages that are of concern. Thiamine is heat sensitive, and being water soluble as well, it leaches out of vegetables and beans during cooking, and so could easily be lost during the manufacture of ready meals. Without adequate labelling, we simply dont know the extent to which this may be occurring. As I have argued, the rapid growth of the ready meals market means there is a strong case for demanding greater information on the vitamin content of these meals.

The whole diet matters

Taking a vitamin supplement may seem an obvious way to boost thiamine intake to help maintain a healthy brain. This may be a good idea for some people, but thiamine unlike most other vitamins is poorly absorbed when taken as a supplement. There is a consensus among nutritionists that a better approach is a healthy diet, not least because multivitamin pills are linked to an increased risk of cancer in some people. Also, it is only with a healthy diet that we can be sure of obtaining the myriad of vitamins, minerals and phytonutrients needed for a healthy brain.

It is probably the wide range of brain-friendly nutrients including thiamine in the Mediterranean diet that makes it so effective at reducing the risk of developing Alzheimers disease. In a way, its a shame that the Mediterranean diet wasnt invented by a drug company as a means to help prevent or delay Alzheimers. If it was, it would probably be one of the most widely marketed and prescribed drugs in the world.

It is not known to what extent thiamine deficiencies are contributing to the rise in Alzheimers disease. But despite the gloomy news about the rising tide of Alzheimers disease, there is certainly no need to feel powerless, as current research suggests that a healthy Mediterranean-style diet containing adequate thiamine can go a long way to help you fend off this disease.

Richard Hoffman, Lecturer in Nutritional Biochemistry, University of Hertfordshire

This article was originally published on The Conversation. Read the original article.

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